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Those who choose AstraZeneca may get mRNA shot for second dose

Dr. Robert Strang says 'there's research going on about the ability to mix vaccine'
022421 - covid vaccine - pfizer
A nurse prepares a dose of COVID-19 vaccine to be administered today, Feb. 24, at the first clinic in a First Nation community in Nova Scotia

With files from the Canadian Press

Nova Scotians who have chosen to get the AstraZeneca vaccine may get either a Pfizer or Moderna shot for their second dose.

"There's research going on about the ability to mix vaccine, so people who got immunized with AstraZeneca, there's research going on about can we give them another vaccine," explained Dr. Robert Strang at a Tuesday briefing.

"There's a line of thinking that it actually .... if their first dose is AstraZeneca, it may be preferable to give them an mRNA vaccine as their second dose."

The chief medical officer of health said it's an evolving science, but "everybody will be able to get their second dose with an appropriate vaccine."

The statement comes just days National Advisory Committee on Immunization (NACI) said the mRNA vaccines from Pfizer-BioNTech and Moderna are "preferred" because they don't carry the remote risk of a blood-clotting syndrome, which appeared to contradict Health Canada's long-standing recommendation that the best vaccine is the first one available.

Three deaths in Canada have been linked to vaccine-induced immune thrombotic thrombocytopenia or VITT.

The most recent case was in New Brunswick.

That province's chief medical officer of health, Dr. Jennifer Russell says the individual in their 60s received the vaccine in mid-April and developed symptoms a week later. She says the person was admitted to hospital and died two days later.

Russell told a news conference today the risk of complications from the vaccine remains very low, between one in 100,000 and one in 250,000 doses.

She said anyone getting the vaccine should monitor for adverse symptoms, including shortness of breath, chest pain, leg swelling, persistent abdominal pain, neurological symptoms such as severe and worsening persistent headaches or blurred vision and skin bruising or tiny blood spots under the skin beyond the site of the injection.

As of April 24, around 1.7 million doses of AstraZeneca had been giving out across the country.

NACI has said Canadians under 30 shouldn't be offered AstraZeneca or the newly approved one dose Johnson & Johnson -- also a viral vector vaccine that carries a remote blood clot risk. 

Here in Nova Scotia, those between the ages of 40 and 64 are eligible to receive the AstraZeneca vaccine. 

When the age bracket was expanded last week in our province to include those between 40 and 54, appointments were quickly snatched up.

Strang said all of the approved vaccines "are good vaccines," but NACI "is not overstating the facts."

"The reality is mRNA vaccines are better vaccines," he said. "We've always said Nova Scotians can have a choice."

"They've been given information about the unique safety risks of the AstraZeneca vaccine, they've been given information around the difference in effectiveness on the vaccines, they've been given information about when in their age group they can expect to an mRNA vaccine, and they can put all that together and make a decision on whether they want to get AstraZeneca or wait to get an mRNA vaccine."


Meghan Groff

About the Author: Meghan Groff

Born in Michigan, raised in Ontario, schooled in Indiana and lives in Nova Scotia; Meghan is the community editor for
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